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改变了传统的男性包皮环切手术概念


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未行包皮环切术男性阴茎人乳头状瘤病毒(HPV)感染的清除降低
Reduced clearance of penile human papillomavirus infection in uncircumcised men
J Infect Dis. 2010 May 1;201(9):1340-3.

Reduced clearance of penile human papillomavirus infection in uncircumcised men.

Hernandez BY, Shvetsov YB, Goodman MT, Wilkens LR, Thompson P, Zhu X, Ning L.

Source

Cancer Research Center of Hawaii, 1236 Lauhala St, Honolulu, HI 96813, USA. brenda@crch.hawaii.edu

Abstract

The relationship between circumcision and the acquisition and clearance of human papillomavirus (HPV) infection was examined in a cohort of 357 men followed up at 2-month intervals for an average of 431 days. There were no differences in HPV acquisition by circumcision status. Clearance of HPV infection, including infection with oncogenic types, was slower in the glans/coronal sulcus of the penis of uncircumcised men than circumcised men. The median duration of HPV infection of the glans/coronal sulcus was significantly longer in uncircumcised men (154 days) than circumcised men (91 days) (P=.04). Circumcision may protect against HPV-associated disease by enhancing the resolution of infection.

PMID: 20350160 [PubMed - indexed for MEDLINE] PMCID: PMC2853736
 
 
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